Background: Cervical cancer remains the most common cancer in women in Eastern Africa. The estimated Incidence of Cervical Cancer was about 42.7 and Mortality rate of 27.6 per 100,000. In Ethiopia, Current estimates indicate that every year 7095 women are diagnosed with cervical cancer and 4732 die from the disease. Due to lack of awareness about the disease, inadequacy or lacking of screening programs in less developed countries-Ethiopia, the incidence of the disease is increasing alarmingly. This study Assessed the Knowledge about cervical cancer and its associated factors among reproductive age women at Robe and Goba towns, Bale zone, south east Ethiopia, 2015. Methodology: A community based cross-sectional survey was conduct from February to May 2015 in Robe & Goba towns, southeast Ethiopia. Three Hundred sixty three households having at least one women aged 15 -49 were included in the study. Systematic sampling method was used to select the households. A structured questionnaire was used to collect the data. Ten trained Urban Health Extension workers were collected the data. Binary and Multiple Logistic regression methods were use to identify independent predictors of the knowledge of women on the cervical cancer.